Description:
The role is in a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit high-value frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
As a key member of our dynamic pharmacology team, reporting to the senior pharmacology manager, you will:
Design and coordinate contract research organization (CRO)-based external pharmacology studies, such as standard PKPD or efficacy, in CDX, PDX or GEMM models.
Build and maintain key vendor relationships. Manage existing CROs and take a role in identification of new vendors, including assessing services, expertise, and costs.
Responsible for initiation and execution of agreements with CROs including master service agreements, statements of work, material transfer agreements, etc.
Manage and track pharmacology studies at CROs, liaise with different functions and project teams within Revolution Medicines.
Creation and/or curation of appropriate databases/logs for tracking study status and data archival.
Facilitate integration of multiple in vivo study data sources into one main database.
Proactively identify, and support implementation of, strategies to enhance efficiencies from study execution through to data analysis and archive
Qualifications:Required Experience, Skills, and Education:
BS/MS degree in relevant scientific discipline and 5+ years of experience in project coordination or management with oncology/pharmacology background in an industry environment.
Rigorous, quantitative, attention to detail, keen to maximize efficiency.
Highly organized, detail-oriented, excellent record keeping skills, and calm under pressure.
Excellent written and verbal communication skills to work with project and departmental teams.
Innovative, proactive and collaborative team-player for our small company environment.
Demonstrated ability to meet project deadlines and work efficiently in a fluid environment.
Have extensive knowledge of cancer pharmacology (preferably with hands-on in vivo pharmacology skills).
Demonstrate experience in data analysis software such as Excel and Prism, experience in Genedata Profiler would be a plus.
Experience with small molecule drug discovery will be a plus.
Experience Level:
Intermediate Level
Please be sure to submit your resume with all applications.
About Actalent:
Actalent connects passion with purpose. Our scalable talent solutions and services capabilities drive value and results and provide the expertise to help our customers achieve more. Every day, our experts around the globe are making an impact. We’re supporting critical initiatives in engineering and sciences that advance how companies serve the world. Actalent promotes consultant care and engagement through experiences that enable continuous development. Our people are the difference. Actalent is an operating company of Allegis Group, the global leader in talent solutions. The company is an equal opportunity employer and will consider all applications without regards to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
About Actalent:
Actalent connects passion with purpose. Our scalable talent solutions and services capabilities drive value and results and provide the expertise to help our customers achieve more. Every day, our experts around the globe are making an impact. We’re supporting critical initiatives in engineering and sciences that advance how companies serve the world. Actalent promotes consultant care and engagement through experiences that enable continuous development. Our people are the difference. Actalent is an operating company of Allegis Group, the global leader in talent solutions.
The company is an equal opportunity employer and will consider all applications without regards to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
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