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Job Description Summary The Paczesny laboratory is seeking highly motivated candidates for a post-doctoral fellowship studying immunotherapy including allogeneic hematopoietic cell transplantation to treat leukemia. The major interests of the lab are in proteomics and biomarkers, graft-versus-host disease and graft-versus leukemia, tumor immunology, novel immunotherapies including cell-based and small molecules, and understanding the alarmin IL33/ST2 axis during inflammatory diseases. In this position, you will have the opportunity to develop and lead projects using several cutting-edge model systems including novel bone marrow transplantation, and xenograft in vivo systems, and primary patient samples. You will also gain extensive experience and training in proteomics, leukemia models, and hematopoietic stem cell transplantation pre-clinical models.
Entity
Medical University of South Carolina (MUSC – Univ)
Worker Type
Employee
Worker Sub-Type
Regular
Cost Center
CC000981 COM M&I Operations CC
Pay Rate Type
Salary
Pay Grade
University-00
Pay Range
$0 – $0 – $0
Scheduled Weekly Hours
40
Work Shift
Job Description
35% – Develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems, and primary patient samples. Each project leading to a presentation at a national meeting as well as
manuscript of impact factor > 6. – (Essential)
35% – Perform immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity assays including for collaborative work on multi-institutional grants. – (Essential)
15% – Train in proteomics, hematopoietic cell transplantation biology, and pre-clinical study development. Similarly the outcomes will lead to a publishable manuscript – (Essential)
15% – Perform other essential duties as requested. These will include maintain animal colonies, collaborate with DLAR to provide the best animal care, update IACUC and IBC protocols, order supplies for the laboratory. – (Essential)
Minimum Experience and Training Requirements: Ph.D. or M.D./Ph.D.
Preferred Experience & Additional Skills: Successful applicants will have a Ph.D. or M.D./Ph.D. with substantial hands-on research experience in immunology; a strong publication record in recognized peer-reviewed journals; experience with animal models of cell adoptive transfer, bone marrow transplantation and/or leukemia is required; experience with multicolor flow cytometry and in immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity assays; be meticulous at planning, executing, and organizing the results for large scale assays. Must also be capable of taking initiative, work independently and in a collaborative setting. Excellent written and verbal communication skills are required, as are excellent organizational skills and knowledge of proper scientific record keeping as well as being comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
Musc
The Medical University of South Carolina (MUSC) is located in the beautiful historic district of Charleston (ranked #1 travel destination in the U.S.) bounded by the Atlantic Ocean and beautiful beaches to the east, and national forests and wildlife refuges to the north and south. MUSC is the state’s top-ranked medical center. The Medical University of South Carolina is a leading medical research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future.
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations.
All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Application Materials Should Be Addressed To
Sophie Paczesny, MD, Ph.D.
Professor of Microbiology and Immunology and Pediatrics
Hollings Cancer Center Biology & Immunology Program co-Leader
SmartState Endowed Chair, Cancer Stem Cell Biology
Medical University of South Carolina
86 Jonathan Lucas, Rm HO612E
Charleston, SC 29425
843-792-1034
Additional Job Description
Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous – 6-8 hours per shift; Frequent – 2-6 hours per shift; Infrequent – 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform ‘pinching’ operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
